Publications (by date):

Representative Publications

Innate Immunity and Asthma Risk in Amish and Hutterite Farm Children.
Stein MM, Hrusch CL, Gozdz J, Igartua C, Pivniouk V, Murray SE, Ledford JG, Marques dos Santos M, Anderson RL, Metwali N, Neilson JW, Maier RM, Gilbert JA, Holbreich M, Thorne PS, Martinez FD, von Mutius E, Vercelli D, Ober C, Sperling AI.
(2016) N Engl J Med. 375(5):411-21. doi: 10.1056/NEJMoa1508749. PMID: 27518660

Genome-Wide Methylation Study Identifies an IL-13-induced Epigenetic Signature in Asthmatic Airways.
Nicodemus-Johnson J, Naughton KA, Sudi J, Hogarth K, Naurekas ET, Nicolae DL, Sperling AI, Solway J, White SR, Ober C.
(2016) Am J Respir Crit Care Med. 193(4):376-85. doi: 10.1164/rccm.201506-1243OC. PMID: 26474238

Integrated analyses of gene expression and genetic association studies in a founder population.
Cusanovich DA, Caliskan M, Billstrand C, Michelini K, Chavarria C, De Leon S, Mitrano A, Lewellyn N, Elias JA, Chupp GL, Lang RM, Shah SJ, Decara JM, Gilad Y, Ober C.
(2016) Hum Mol Genet. . PMID: 26931462

Leveraging gene-environment interactions and endotypes for asthma gene discovery.
Bønnelykke K, Ober C.
(2016) J Allergy Clin Immunol. 137(3):667-79. doi:10.1016/j.jaci.2016.01.006. Review. PMID: 26947980

Expression Quantitative Trait Locus Mapping Studies in Mid-secretory Phase Endometrial Cells Identifies HLA-F and TAP2 as Fecundability-Associated Genes.
Burrows CK, Kosova G, Herman C, Patterson K, Hartmann KE, Velez Edwards DR, Stephenson MD, Lynch VJ, Ober C.
(2016) PLoS Genet. 12(7):e1005858. doi: 10.1371/journal.pgen.1005858. eCollection 2016 Jul. PMID: 27447835

Genetic associations with viral respiratory illnesses and asthma control in children.
Loisel DA, Du G, Ahluwalia TS, Tisler CJ, Evans MD, Myers RA, Gangnon RE, Kreiner-Møller E, Bønnelykke K, Bisgaard H, Jackson DJ, Lemanske RF Jr, Nicolae DL, Gern JE, Ober C.
(2016) Clin Exp Allergy. 46(1):112-24. doi: 10.1111/cea.12642. PMID: 26399222

Genome-wide association study of recalcitrant atopic dermatitis in Korean children.
Kim, K.W., Myers, R.A., Lee, J.H., Igartua, C., Lee, K.E., Kim, Y.H., Kim, E.J., Yoon, D., Lee, J.S., Hirota, T., Tamari, M., Takahashi, A., Kubo, M., Choi, J.M., Kim, K.E., Nicolae, D.L., Ober, C. & Sohn, M.H.
(2015) J Allergy Clin Immunol. 678-684 e4. PMID: 4562879

Genome-Wide association studies of the human gut microbiota.
Davenport, E.R., Cusanovich, D.A., Michelini, K., Barreiro, L.B., Ober, C. & Gilad, Y.
(2015) PLoS One. 10(11):e0140301. doi: 10.1371/journal.pone.0140301. PMID: 26528553

Host genetic variation influences gene expression response to rhinovirus infection.
Çalışkan M, Baker SW, Gilad Y, Ober C.
(2015) PLoS Genet. 11(4):e1005111. doi: 10.1371/journal.pgen.1005111. PMID: 25874939

PRIMAL: Fast and accurate pedigree-based imputation from sequence data in a founder population.
Livne OE, Han L, Alkorta-Aranburu G, Wentworth-Sheilds W, Abney M, Ober C, Nicolae DL.
(2015) PLoS Comput Biol. 11(3):e1004139. doi:10.1371/journal.pcbi.1004139. PMID: 25735005

An estimate of the average number of recessive lethal mutations carried by humans. Genetics. 2015
Gao Z, Waggoner D, Stephens M, Ober C, Przeworski M.
(2015) genetics. 199(4):1243-54. doi: 10.1534/genetics.114.173351. Epub 2015 Feb 18. PMID: 25697177

Ethnic-specific associations of rare and low-frequency DNA sequence variants with asthma.
Igartua C, Myers RA, Mathias RA, Pino-Yanes M, Eng C, Graves PE, Levin AM, Del-Rio-Navarro BE, Jackson DJ, Livne OE, Rafaels N, Edlund CK, Yang JJ, Huntsman S, Salam MT, Romieu I, Mourad R, Gern JE, Lemanske RF, Wyss A, Hoppin JA, Barnes KC, Burchard EG, Gauderman WJ, Martinez FD, Raby BA, Weiss ST, Williams LK, London SJ, Gilliland FD, Nicolae DL, Ober C.
(2015) Nat Commun. 6:5965. doi: 10.1038/ncomms6965. PMID: 25591454

Disclosure of genetic research results to members of a founder population.
Anderson RL, Murray K, Chong JX, Ouwenga R, Antillon M, Chen P, Diaz de Leon L, Swoboda KJ, Lester LA, Das S, Ober C, Waggoner DJ.
(2014) Journal of genetic counseling. 23(6):984-91. PMID: 24777552

Whole-genome sequencing of individuals from a founder population identifies candidate genes for asthma.
Campbell CD, Mohajeri K, Malig M, Hormozdiari F, Nelson B, Du G, Patterson KM, Eng C, Torgerson DG, Hu D, Herman C, Chong JX, Ko A, O'Roak BJ, Krumm N, Vives L, Lee C, Roth LA, Rodriguez-Cintron W, Rodriguez-Santana J, Brigino-Buenaventura E, Davis A, Meade K, LeNoir MA, Thyne S, Jackson DJ, Gern JE, Lemanske RF, Jr., Shendure J, Abney M, Burchard EG, Ober C, Eichler EE.
(2014) PLoS One. 9(8):e104396. PMID: 4130548

The effect of freeze-thaw cycles on gene expression levels in lymphoblastoid cell lines.
Caliskan M, Pritchard JK, Ober C, Gilad Y.
(2014) PLoS One. 9(9):e107166. PMID: 4156430

Genome-wide interaction studies reveal sex-specific asthma risk alleles.
Myers RA, Scott NM, Gauderman WJ, Qiu W, Mathias RA, Romieu I, Levin AM, Pino-Yanes M, Graves PE, Villarreal AB, Beaty TH, Carey VJ, Croteau-Chonka DC, Del Rio Navarro B, Edlund C, Hernandez-Cadena L, Navarro-Olivos E, Padhukasahasram B, Salam MT, Torgerson DG, Van den Berg DJ, Vora H, Bleecker ER, Meyers DA, Williams LK, Martinez FD, Burchard EG, Barnes KC, on behalf of G, Gilliland FD, Weiss ST, London SJ, Raby BA, Ober C, Nicolae DL.
(2014) Hum Mol Genet. 23(19):5251-9. PMID:

Lifecourse Epidemiology C, Casula S, Biino G, Dizier MH, Pin I, Matran R, Lathrop M, Pirastu M, Demenais F, Ober C. A Common variant in RAB27A gene is associated with fractional exhaled nitric oxide levels in adults.
Bouzigon E, Nadif R, Thompson EE, Concas MP, Kuldanek S, Du G, Brossard M, Lavielle N, Sarnowski C, Vaysse A, Dessen P, van der Valk RJ, Duijts L, Henderson AJ, Jaddoe VW, de Jongste JC, consortium G, Genetics EA,
(2014) Clin Exp Allergy. . PMID:

Seasonal variation in human gut microbiome composition.
Davenport ER, Mizrahi-Man O, Michelini K, Barreiro LB, Ober C, Gilad Y.
(2014) PLoS One. 9(3):e90731. doi: 10.1371/journal.pone.0090731. eCollection 2014. PMID: 24618913

Variants in DPF3 and DSCAML1 are associated with sperm morphology.
Kosova G, Hotaling JM, Ohlander S, Niederberger C, Prins GS, Ober C.
(2014) J Assist Reprod Genet. 31(2):131-7. doi: 10.1007/s10815-013-0140-9. Epub 2013 Nov 26. PMID: 24271036

Genome-wide association study of lung function phenotypes in a founder population.
Yao TC, Du G, Han L, Sun Y, Hu D, Yang JJ, Mathias R, Roth LA, Rafaels N, Thompson EE, Loisel DA, Anderson R, Eng C, Arruabarrena Orbegozo M, Young M, Klocksieben JM, Anderson E, Shanovich K, Lester LA, Williams LK, Barnes KC, Burchard EG, Nicolae DL, Abney M, Ober C.
(2014) J Allergy Clin Immunol. 133(1):248-55.e1-10. doi: 10.1016/j.jaci.2013.06.018. Epub 2013 Aug 6. PMID: 23932459

Mutation for nonsyndromic mental retardation in the trans-2-enoyl-CoA reductase TER gene involved in fatty acid elongation impairs the enzyme activity and stability, leading to change in sphingolipid profile.
Abe K, Ohno Y, Sassa T, Taguchi R, Çalışkan M, Ober C, Kihara A.
(2013) J Biol Chem. 288(51):36741-9. doi: 10.1074/jbc.M113.493221. Epub 2013 Nov 12. PMID: 24220030

Homozygous founder mutation in desmocollin-2 (DSC2) causes arrhythmogenic cardiomyopathy in the Hutterite population.
Gerull B, Kirchner F, Chong JX, Tagoe J, Chandrasekharan K, Strohm O, Waggoner D, Ober C, Duff HJ.
(2013) Circ Cardiovasc Genet. 6(4):327-36. doi: 10.1161/CIRCGENETICS.113.000097. Epub 2013 Jul 17. PMID: 23863954

Recessive TRAPPC11 mutations cause a disease spectrum of limb girdle muscular dystrophy and myopathy with movement disorder and intellectual disability.
Bögershausen N, Shahrzad N, Chong JX, von Kleist-Retzow JC, Stanga D, Li Y, Bernier FP, Loucks CM, Wirth R, Puffenberger EG, Hegele RA, Schreml J, Lapointe G, Keupp K, Brett CL, Anderson R, Hahn A, Innes AM, Suchowersky O, Mets MB, Nürnberg G, McLeod DR, Thiele H, Waggoner D, Altmüller J, Boycott KM, Schoser B, Nürnberg P, Ober C, Heller R, Parboosingh JS, Wollnik B, Sacher M, Lamont RE.
(2013) Am J Hum Genet. 93(1):181-90. doi: 10.1016/j.ajhg.2013.05.028. Epub 2013 Jul 3. PMID: 3710757

Intellectual disability associated with a homozygous missense mutation in THOC6.
Beaulieu CL, Huang L, Innes AM, Akimenko MA, Puffenberger EG, Schwartz C, Jerry P, Ober C, Hegele RA, McLeod DR, Schwartzentruber J, Majewski J, Bulman DE, Parboosingh JS, Boycott KM.
(2013) Orphanet J Rare Dis. 8(1):62. PMID: 23621916

Human spermatogenic failure purges deleterious mutation load from the autosomes and both sex chromosomes, including the gene DMRT1.
Lopes AM, Aston KI, Thompson E, Carvalho F, Gonçalves J, Huang N, Matthiesen R, Noordam MJ, Quintela I, Ramu A, Seabra C, Wilfert AB, Dai J, Downie JM, Fernandes S, Guo X, Sha J, Amorim A, Barros A, Carracedo A, Hu Z, Hurles ME, Moskovtsev S, Ober C, Paduch DA, Schiffman JD, Schlegel PN, Sousa M, Carrell DT, Conrad DF.
(2013) PLoS Genet. 9(3):e1003349. doi: 10.1371/journal.pgen.1003349. Epub 2013 Mar 21. PMID: 23555275

Maternal asthma and microRNA regulation of soluble HLA-G in the airway.
Nicodemus-Johnson J, Laxman B, Stern RK, Sudi J, Tierney CN, Norwick L, Hogarth DK, McConville JF, Naureckas ET, Sperling AI, Solway J, Krishnan JA, Nicolae DL, White SR, Ober C.
(2013) J Allergy Clin Immunol. 131(6):1496-1503.e4. PMID: 23534973

Rhinovirus wheezing illness and genetic risk of childhood-onset asthma.
Calışkan M, Bochkov YA, Kreiner-Møller E, Bønnelykke K, Stein MM, Du G, Bisgaard H, Jackson DJ, Gern JE, Lemanske RF Jr, Nicolae DL, Ober C.
(2013) N Engl J Med. 368(15):1398-407. PMID: 23534543

The maternal HLA-G 1597ΔC null mutation is associated with increased risk of pre-eclampsia and reduced HLA-G expression during pregnancy in African-American women.
Loisel DA, Billstrand C, Murray K, Patterson K, Chaiworapongsa T, Romero R, Ober C.
(2013) Mol Hum Reprod. 19(3):144-52. PMID: 23002110

Maternal microchimerism protects against the development of asthma.
Thompson EE, Myers RA, Du G, Aydelotte TM, Tisler CJ, Stern DA, Evans MD, Graves PE, Jackson DJ, Martinez FD, Gern JE, Wright AL, Lemanske RF, Ober C.
(2013) J Allergy Clin Immunol. . PMID: 23434286

The ABO blood group is a trans-species polymorphism in primates.
Ségurel L, Thompson EE, Flutre T, Lovstad J, Venkat A, Margulis SW, Moyse J, Ross S, Gamble K, Sella G, Ober C, Przeworski M.
(2012) Proc Natl Acad Sci U S A. 109(45):18493-8. PMID: 23091028

Further replication studies of the EVE Consortium meta-analysis identifies 2 asthma risk loci in European Americans.
Myers RA, Himes BE, Gignoux CR, Yang JJ, Gauderman WJ, Rebordosa C, Xie J, Torgerson DG, Levin AM, Baurley J, Graves PE, Mathias RA, Romieu I, Roth LA, Conti D, Avila L, Eng C, Vora H, LeNoir MA, Soto-Quiros M, Liu J, Celedón JC, Farber HJ, Kumar R, Avila PC, Meade K, Serebrisky D, Thyne S, Rodriguez-Cintron W, Rodriguez-Santana JR, Borrell LN, Lemanske RF Jr, Bleecker ER, Meyers DA, London SJ, Barnes KC, Raby BA, Martinez FD, Gilliland FD, Williams LK, Burchard EG, Weiss ST, Nicolae DL, Ober C.
(2012) J Allergy Clin Immunol. 130(6):1294-301. PMID: 23040885

Estimating the human mutation rate using autozygosity in a founder population.
Campbell CD, Chong JX, Malig M, Ko A, Dumont BL, Han L, Vives L, O'Roak BJ, Sudmant PH, Shendure J, Abney M, Ober C, Eichler EE.
(2012) Nat Genet. 44(11):1277-81. PMID: 23001126

A population-based study of autosomal-recessive disease-causing mutations in a founder population.
Chong JX, Ouwenga R, Anderson RL, Waggoner DJ, Ober C.
(2012) Am J Hum Genet. 91(4):608-20. PMID: 22981120

Increased protein-coding mutations in the mitochondrial genome of African American women with preeclampsia.
Ding D, Scott NM, Thompson EE, Chaiworapongsa T, Torres R, Billstrand C, Murray K, Dexheimer PJ, Ismail M, Kay H, Levy S, Romero R, Lindheimer MD, Nicolae DL, Ober C.
(2012) Reprod Sci. 19(12):1343-51. PMID: 22902742

HLA-G polymorphisms and soluble HLA-G protein levels in women with recurrent pregnancy loss from Basrah province in Iraq.
Jassem RM, Shani WS, Loisel DA, Sharief M, Billstrand C, Ober C.
(2012) Hum Immunol. 73(8):811-7. PMID: 22651916

Genome-wide association study identifies candidate genes for male fertility traits in humans.
Kosova G, Scott NM, Niederberger C, Prins GS, Ober C.
(2012) Am J Hum Genet. 90(6):950-61. PMID: 22633400

Genome-wide ancestry association testing identifies a common European variant on 6q14.1 as a risk factor for asthma in African American subjects.
Torgerson DG, Capurso D, Ampleford EJ, Li X, Moore WC, Gignoux CR, Hu D, Eng C, Mathias RA, Busse WW, Castro M, Erzurum SC, Fitzpatrick AM, Gaston B, Israel E, Jarjour NN, Teague WG, Wenzel SE, Rodríguez-Santana JR, Rodríguez-Cintrón W, Avila PC, Ford JG, Barnes KC, Burchard EG, Howard TD, Bleecker ER, Meyers DA, Cox NJ, Ober C, Nicolae DL.
(2012) J Allergy Clin Immunol. 130(3):622-9 e9. PMID: 22607992

XM: association testing on the X-chromosome in case-control samples with related individuals.
Thornton T, Zhang Q, Cai X, Ober C, McPeek MS.
(2012) Genet Epidemiol. 36(5):438-50. doi: 10.1002/gepi.21638. PMID: 22552845

Evaluating the evidence for transmission distortion in human pedigrees.
Meyer WK, Arbeithuber B, Ober C, Ebner T, Tiemann-Boege I, Hudson RR, Przeworski M.
(2012) Genetics. 191(1):215-32. PMID: 22377632

Accurate imputation of rare and common variants in a founder population from a small number of sequenced individuals.
Uricchio LH, Chong JX, Ross KD, Ober C, Nicolae DL.
(2012) Genet Epidemiol. 36(4):312-9. doi: 10.1002/gepi.21623. PMID: 22460724

The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.
Cusanovich DA, Billstrand C, Zhou X, Chavarria C, De Leon S, Michelini K, Pai AA, Ober C, Gilad Y.
(2012) Hum Mol Genet. 21(9):2111-23. PMID: 22286170

Resequencing candidate genes implicates rare variants in asthma susceptibility.
Torgerson DG, Capurso D, Mathias RA, Graves PE, Hernandez RD, Beaty TH, Bleecker ER, Raby BA, Meyers DA, Barnes KC, Weiss ST, Martinez FD, Nicolae DL, Ober C.
(2012) Am J Hum Genet. 90(2):273-81. PMID: 22325360

Rising prevalence of asthma is sex-specific in a US farming population.
Motika CA, Papachristou C, Abney M, Lester LA, Ober C.
(2011) J Allergy Clin Immunol. 128(4):774-9. Epub 2011 Aug 15. PMID: 21840584

Meta-analysis of genome-wide association studies of asthma in ethnically diverse North American populations.
Torgerson DG, Ampleford EJ, Chiu GY, Gauderman WJ, Gignoux CR, Graves PE, Himes BE, Levin AM, Mathias RA, Hancock DB, Baurley JW, Eng C, Stern DA, Celedón JC, Rafaels N, Capurso D, Conti DV, Roth LA, Soto-Quiros M, Togias A, Li X, Myers RA, Romieu I, Van Den Berg DJ, Hu D, Hansel NN, Hernandez RD, Israel E, Salam MT, Galanter J, Avila PC, Avila L, Rodriquez-Santana JR, Chapela R, Rodriguez-Cintron W, Diette GB, Adkinson NF, Abel RA, Ross KD, Shi M, Faruque MU, Dunston GM, Watson HR, Mantese VJ, Ezurum SC, Liang L, Ruczinski I, Ford JG, Huntsman S, Chung KF, Vora H, Li X, Calhoun WJ, Castro M, Sienra-Monge JJ, del Rio-Navarro B, Deichmann KA, Heinzmann A, Wenzel SE, Busse WW, Gern JE, Lemanske RF Jr, Beaty TH, Bleecker ER, Raby BA, Meyers DA, London SJ; Mexico City Childhood Asthma Study (MCAAS), Gilliland FD; Children's Health Study (CHS) and HARBORS study, Burchard EG; Genetics of Asthma in Latino Americans (GALA) Study, Study of Genes-Environment and Admixture in Latino Americans (GALA2) and Study of African Americans, Asthma, Genes & Environments (SAGE), Martinez FD; Childhood Asthma Research and Education (CARE) Network, Weiss ST; Childhood Asthma Management Program (CAMP), Williams LK; Study of Asthma Phenotypes and Pharmacogenomic Interactions by Race-Ethnicity (SAPPHIRE), Barnes KC; Genetic Research on Asthma in African Diaspora (GRAAD) Study, Ober C, Nicolae DL.
(2011) Nat Genet. 43(9):887-92. doi: 10.1038/ng.888. PMID: 21804549

IFNG genotype and sex interact to influence the risk of childhood asthma.
Loisel DA, Tan Z, Tisler CJ, Evans MD, Gangnon RE, Jackson DJ, Gern JE, Lemanske RF Jr, Ober C.
(2011) J Allergy Clin Immunol. 128(3):524-31. Epub 2011 Jul 27. PMID: 2179857

The genetics of asthma and allergic disease: a 21st century perspective.
Ober C, Yao TC.
(2011) Immunol Rev. 242(1):10-30. doi:10.1111/j.1600-065X.2011.01029.x. PMID: 21682736

Exome sequencing and the genetics of intellectual disability.
Topper S, Ober C, Das S.
(2011) Clin Genet. 80(2):117-26. doi:10.1111/j.1399-0004.2011.01720.x. Epub 2011 Jun 15. PMID: 21627642

A common spinal muscular atrophy deletion mutation is present on a single founder haplotype in the US Hutterites.
Chong JX, Oktay AA, Dai Z, Swoboda KJ, Prior TW, Ober C.
(2011) Eur J Hum Genet. 19(10):1045-51. doi: 10.1038/ejhg.2011.85. Epub 2011 May 25. PMID: 21610747

Genetic variance components estimation for binary traits using multiple related individuals.
Papachristou C, Ober C, Abney M.
(2011) Genet Epidemiol. 35(5):291-302. doi: 10.1002/gepi.20577. Epub 2011 Apr 4. PMID: 21465547

The effects of EBV transformation on gene expression levels and methylation profiles.
Caliskan M, Cusanovich DA, Ober C, Gilad Y.
(2011) Hum Mol Genet. 20(8):1643-52. Epub 2011 Feb 2. PMID: 21289059

Gene-environment interactions in human disease: nuisance or opportunity?
Ober C, Vercelli D.
(2011) Trends Genet. 27(3):107-15. Epub 2011 Jan 7. PMID: 21216485

Exome Sequencing Reveals a Novel Mutation for Autosomal Recessive Nonsyndromic Mental Retardation in the TECR Gene on Chromosome 19p13.
Caliskan M, Chong JX, Uricchio L, Anderson R, Chen P, Sougnez C, Garimella K, Gabriel SB, Depristo MA, Shakir K, Matern D, Das S, Waggoner D, Nicolae DL, Ober C.
(2011) Hum Mol Genet. . PMID: 21212097

Sequence variation in the IL4 gene and resistance to Trypanosoma cruzi infection in Bolivians.
Alvarado Arnez LE, Venegas EN, Ober C, Thompson EE.
(2011) J Allergy Clin Immunol. 127(1):279-282.e3. PMID: 21211660

Blood groups in the species survival plan(R), European endangered species program, and managed in situ populations of bonobo (Pan paniscus), common chimpanzee (Pan troglodytes), gorilla (Gorilla ssp.), and orangutan (Pongo pygmaeus ssp.).
Gamble KC, Moyse JA, Lovstad JN, Ober CB, Thompson EE.
(2011) Zoo Biol. 30(4):427-44. doi: 10.1002/zoo.20348. Epub 2010 Sep 17. PMID: 20853409

The CFTR Met 470 allele is associated with lower birth rates in fertile men from a population isolate.
Kosova G, Pickrell JK, Kelley JL, McArdle PF, Shuldiner AR, Abney M, Ober C.
(2010) PLoS Genet. 6(6):e1000974. PMID: 20532200

Husain AN, Ford JG, Garcia JG. Functional variants of the sphingosine-1-phosphate receptor 1 gene associate with asthma susceptibility.
Sun X, Ma SF, Wade MS, Flores C, Pino-Yanes M, Moitra J, Ober C, Kittles R,
(2010) J Allergy Clin Immunol. 126(2):241-9, 249.e1-3. Epub 2010 Jul 10. PMID: 20624651

Getting from Genes to Function in Lung Disease: An NHLBI Workshop Report.
Ober C, Butte AJ, Elias JA, Lusis AJ, Gan W, Banks-Schlegel S, Schwartz D.
(2010) Am J Respir Crit Care Med. 182(6):732-7. PMID: 20558629

Levels of soluble human leukocyte antigen-G are increased in asthmatic airways.
White SR, Loisel DA, McConville JF, Stern R, Tu Y, Marroquin BA, Noth I, Ober C.
(2010) Eur Respir J. 35(4):925-7. PMID: 20356990

PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice.
Baudat F, Buard J, Grey C, Fledel-Alon A, Ober C, Przeworski M, Coop G, de Massy B.
(2010) Science. 327(5967):836-40. Epub 2009 Dec 31. PMID: 20044539

Shades of gray: a comparison of linkage disequilibrium between Hutterites and Europeans.
Thompson EE, Sun Y, Nicolae D, Ober C.
(2010) Genet Epidemiol. 34(2):133-9. PMID: 19697328

Sequencing the IL4 locus in African Americans implicates rare noncoding variants in asthma susceptibility.
Haller G, Torgerson DG, Ober C, Thompson EE.
(2009) J Allergy Clin Immunol. 124(6):1204-9.e9. Epub. PMID: 19910025

Drawing the history of the Hutterite population on a genetic landscape: inference from Y-chromosome and mtDNA genotypes.
Pichler I, Fuchsberger C, Platzer C, Calişkan M, Marroni F, Pramstaller PP, Ober C.
(2010) Eur J Hum Genet. 18(4):463-70. Epub 2009 Oct 21. PMID: 19844259

Sequence variations at the human leukocyte antigen-linked olfactory receptor cluster do not influence female preferences for male odors.
Thompson EE, Haller G, Pinto JM, Sun Y, Zelano B, Jacob S, McClintock MK, Nicolae DL, Ober C.
(2010) Hum Immunol. 71(1):100-3. Epub. PMID: 19833159

Colloquium papers: Heritability of reproductive fitness traits in a human population.
Kosova G, Abney M, Ober C.
(2010) Proc Natl Acad Sci U S A. 107 Suppl 1:1772-8. Epub 2009 Oct 12. PMID: 19822755

Broad-scale recombination patterns underlying proper disjunction in humans.
Fledel-Alon A, Wilson DJ, Broman K, Wen X, Ober C, Coop G, Przeworski M.
(2009) PLoS Genet. 5(9):e1000658. Epub 2009 Sep 18. PMID: 19763175

The chitinase and chitinase-like proteins: a review of genetic and functional studies in asthma and immune-mediated diseases.
Ober C, Chupp GL.
(2009) Curr Opin Allergy Clin Immunol. 9(5):401-8. PMID: 19644363

(Too) great expectations: the challenges in replicating asthma disease genes.
Nicolae DL, Ober C.
(2009) Am J Respir Crit Care Med. 179(12):1078-9. PMID: 19498061

Linkage analysis with dense SNP maps in isolated populations.
Bellenguez C, Ober C, Bourgain C.
(2009) Hum Hered. 68(2):87-97. Epub 2009 Apr 9. PMID: 19365135

Inverted duplications on acentric markers: mechanism of formation.
Murmann AE, Conrad DF, Mashek H, Curtis CA, Nicolae RI, Ober C, Schwartz S.
(2009) Hum Mol Genet. 18(12):2241-56. Epub 2009 Mar 31. PMID: 19336476

Genome-wide association study of plasma lipoprotein(a) levels identifies multiple genes on chromosome 6q.
Ober C, Nord AS, Thompson EE, Pan L, Tan Z, Cusanovich D, Sun Y, Nicolae R, Edelstein C, Schneider DH, Billstrand C, Pfaffinger D, Phillips N, Anderson RL, Philips B, Rajagopalan R, Hatsukami TS, Rieder MJ, Heagerty PJ, Nickerson DA, Abney M, Marcovina S, Jarvik GP, Scanu AM, Nicolae DL.
(2009) J Lipid Res. 50(5):798-806. PMID: 19124843

Whole-genome association study identifies STK39 as a hypertension susceptibility gene.
Wang Y, O'Connell JR, McArdle PF, Wade JB, Dorff SE, Shah SJ, Shi X, Pan L, Rampersaud E, Shen H, Kim JD, Subramanya AR, Steinle NI, Parsa A, Ober CC, Welling PA, Chakravarti A, Weder AB, Cooper RS, Mitchell BD, Shuldiner AR, Chang YP.
(2009) Proc Natl Acad Sci USA. 106(1):226-31. PMID: 19114657

Sex-specific genetic architecture of human disease.
Ober C, Loisel DA, Gilad Y.
(2008) Nat Rev Genet. 9(12):911-22. PMID: 19002143

A genomewide screen for chronic rhinosinusitis genes identifies a locus on chromosome 7q.
Pinto JM, Hayes MG, Schneider D, Naclerio RM, Ober C.
(2008) Laryngoscope. 118(11):2067-72. PMID: 18622306

A multiple splitting approach to linkage analysis in large pedigrees identifies a linkage to asthma on chromosome 12.
Bellenguez C, Ober C, Bourgain C.
(2009) Genet Epidemiol. 33(3):207-16. PMID: 18839415

A Genomewide Screen for Chronic Rhinosinusitis Genes Identifies a Locus on Chromosome 7q.
Pinto JM, Hayes MG, Schneider D, Naclerio RM, Ober C.
(2008) Laryngoscope. 118(11):2067-72. PMID: 18622306

A common cortactin gene variation confers differential susceptibility to severe asthma.
Ma SF, Flores C, Wade MS, Dudek SM, Nicolae DL, Ober C, Garcia JG.
(2008) Genet Epidemiol. 32(8):757-66. PMID: 18521921

Fine mapping of a locus for nonsyndromic mental retardation on chromosome 19p13.
Nolan DK, Chen P, Das S, Ober C, Waggoner D.
(2008) Am J Med Genet A. 146A(11):1414-22. PMID: 18446860

Effect of variation in CHI3L1 on serum YKL-40 level, risk of asthma, and lung function.
Ober C, Tan Z, Sun Y, Possick JD, Pan L, Nicolae R, Radford S, Parry RR, Heinzmann A, Deichmann KA, Lester LA, Gern JE, Lemanske RF Jr, Nicolae DL, Elias JA, Chupp GL.
(2008) N Engl J Med. 358(16):1682-91. Epub 2008 Apr 9. PMID: 18403759

A genome-wide screen for hyposmia susceptibility Loci.
Pinto JM, Thanaviratananich S, Hayes MG, Naclerio RM, Ober C.
(2008) Chem Senses. 33(4):319-29. Epub 2008 Feb 2. PMID: 18245794

High-resolution mapping of crossovers reveals extensive variation in fine-scale recombination patterns among humans.
Coop G, Wen X, Ober C, Pritchard JK, Przeworski M.
(2008) Science. 319(5868):1395-8. Epub 2008 Jan 31. PMID: 18239090

Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.
Gudmundsson J, Sulem P, Rafnar T, Bergthorsson JT, Manolescu A, Gudbjartsson D, Agnarsson BA, Sigurdsson A, Benediktsdottir KR, Blondal T, Jakobsdottir M, Stacey SN, Kostic J, Kristinsson KT, Birgisdottir B, Ghosh S, Magnusdottir DN, Thorlacius S, Thorleifsson G, Zheng SL, Sun J, Chang BL, Elmore JB, Breyer JP, McReynolds KM, Bradley KM, Yaspan BL, Wiklund F, Stattin P, Lindström S, Adami HO, McDonnell SK, Schaid DJ, Cunningham JM, Wang L, Cerhan JR, St Sauver JL, Isaacs SD, Wiley KE, Partin AW, Walsh PC, Polo S, Ruiz-Echarri M, Navarrete S, Fuertes F, Saez B, Godino J, Weijerman PC, Swinkels DW, Aben KK, Witjes JA, Suarez BK, Helfand BT, Frigge ML, Kristjansson K, Ober C, Jonsson E, Einarsson GV, Xu J, Gronberg H, Smith JR, Thibodeau SN, Isaacs WB, Catalona WJ, Mayordomo JI, Kiemeney LA, Barkardottir RB, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K.
(2008) Nat Genet. 40(3):281-3. Epub 2008 Feb 10. PMID: 18264098

Empirical data about women's attitudes towards a hypothetical pediatric biobank.
Neidich AB, Joseph JW, Ober C, Ross LF.
(2008) Am J Med Genet A. 146(3):297-304. PMID: 18205141

Empirical data about women's attitudes toward a biobank focused on pregnancy outcomes.
Joseph JW, Neidich AB, Ober C, Ross LF.
(2008) Am J Med Genet A. 146(3):305-11. PMID: 18203186

CFTR mutations and reproductive outcomes in a population isolate.
Gallego Romero I, Ober C.
(2008) Hum Genet. 122(6):583-8. Epub 2007 Sep 28. PMID: 17901983

Allele-specific targeting of microRNAs to HLA-G and risk of asthma.
Tan Z, Randall G, Fan J, Camoretti-Mercado B, Brockman-Schneider R, Pan L, Solway J, Gern JE, Lemanske RF, Nicolae D, Ober C.
(2007) Am J Hum Genet. 81(4):829-34. Epub 2007 Aug 20. Erratum in: Am J Hum Genet. 2008 Jan;82(1):251. PMID: 17847008

Two variants on chromosome 17 confer prostate cancer risk, and the one in TCF2 protects against type 2 diabetes.
Gudmundsson J, Sulem P, Steinthorsdottir V, Bergthorsson JT, Thorleifsson G, Manolescu A, Rafnar T, Gudbjartsson D, Agnarsson BA, Baker A, Sigurdsson A, Benediktsdottir KR, Jakobsdottir M, Blondal T, Stacey SN, Helgason A, Gunnarsdottir S, Olafsdottir A, Kristinsson KT, Birgisdottir B, Ghosh S, Thorlacius S, Magnusdottir D, Stefansdottir G, Kristjansson K, Bagger Y, Wilensky RL, Reilly MP, Morris AD, Kimber CH, Adeyemo A, Chen Y, Zhou J, So WY, Tong PC, Ng MC, Hansen T, Andersen G, Borch-Johnsen K, Jorgensen T, Tres A, Fuertes F, Ruiz-Echarri M, Asin L, Saez B, van Boven E, Klaver S, Swinkels DW, Aben KK, Graif T, Cashy J, Suarez BK, van Vierssen Trip O, Frigge ML, Ober C, Hofker MH, Wijmenga C, Christiansen C, Rader DJ, Palmer CN, Rotimi C, Chan JC, Pedersen O, Sigurdsson G, Benediktsson R, Jonsson E, Einarsson GV, Mayordomo JI, Catalona WJ, Kiemeney LA, Barkardottir RB, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K.
(2007) Nat Genet. 39(8):977-83. Epub 2007 Jul 1. PMID: 17603485

Correlation of intergenerational family sizes suggests a genetic component of reproductive fitness.
Pluzhnikov A, Nolan DK, Tan Z, McPeek MS, Ober C.
(2007) Am J Hum Genet. 81(1):165-9. Epub 2007 May 2. PMID: 17564973

Integrin beta 3 genotype influences asthma and allergy phenotypes in the first 6 years of life.
Thompson EE, Pan L, Ostrovnaya I, Weiss LA, Gern JE, Lemanske RF Jr, Nicolae DL, Ober C.
(2007) J Allergy Clin Immunol. 119(6):1423-9. PMID: 17556058

Heritability estimation of sex-specific effects on human quantitative traits.
Pan L, Ober C, Abney M.
(2007) Genet Epidemiol. 31(4):338-47. PMID: 17323368

A variant of the myosin light chain kinase gene is associated with severe asthma in African Americans.
Flores C, Ma SF, Maresso K, Ober C, Garcia JG.
(2007) Genet Epidemiol. 31(4):296-305. PMID: 17266121

Genome-wide association study identifies a second prostate cancer susceptibility variant at 8q24.
Gudmundsson J, Sulem P, Manolescu A, Amundadottir LT, Gudbjartsson D, Helgason A, Rafnar T, Bergthorsson JT, Agnarsson BA, Baker A, Sigurdsson A, Benediktsdottir KR, Jakobsdottir M, Xu J, Blondal T, Kostic J, Sun J, Ghosh S, Stacey SN, Mouy M, Saemundsdottir J, Backman VM, Kristjansson K, Tres A, Partin AW, Albers-Akkers MT, Godino-Ivan Marcos J, Walsh PC, Swinkels DW, Navarrete S, Isaacs SD, Aben KK, Graif T, Cashy J, Ruiz-Echarri M, Wiley KE, Suarez BK, Witjes JA, Frigge M, Ober C, Jonsson E, Einarsson GV, Mayordomo JI, Kiemeney LA, Isaacs WB, Catalona WJ, Barkardottir RB, Gulcher JR, Thorsteinsdottir U, Kong A, Stefansson K.
(2007) Nat Genet. 39(5):631-7. Epub 2007 Apr 1. PMID: 17401366

The development and validation of the Indigenous Risk Impact Screen (IRIS): a 13-item screening instrument for alcohol and drug and mental health risk.
Schlesinger CM, Ober C, McCarthy MM, Watson JD, Seinen A.
(2007) Drug Alcohol Rev. 26(2):109-17. PMID: 17364845

Genetic studies of stuttering in a founder population.
Wittke-Thompson JK, Ambrose N, Yairi E, Roe C, Cook EH, Ober C, Cox NJ.
(2007) J Fluency Disord. 32(1):33-50. Epub 2006 Dec 30. PMID: 17276504

Variation in ITGB3 is associated with whole-blood serotonin level and autism susceptibility.
Weiss LA, Kosova G, Delahanty RJ, Jiang L, Cook EH, Ober C, Sutcliffe JS.
(2006) Eur J Hum Genet. 14(8):923-31. Epub 2006 May 17. PMID: 16724005

ITGB3 shows genetic and expression interaction with SLC6A4.
Weiss LA, Ober C, Cook EH Jr.
(2006) Hum Genet. 120(1):93-100. Epub 2006 May 24. PMID: 16721604

Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci.
Kurz T, Hoffjan S, Hayes MG, Schneider D, Nicolae R, Heinzmann A, Jerkic SP, Parry R, Cox NJ, Deichmann KA, Ober C.s
(2006) J Allergy Clin Immunol. 118(2):396-402. Epub 2006 Jun 9. PMID: 16890764

The miscarriage-associated HLA-G -725G allele influences transcription rates in JEG-3 cells.
Ober C, Billstrand C, Kuldanek S, Tan Z.
(2006) Hum Reprod. 21(7):1743-8. Epub 2006 Feb 24. PMID: 16501035

A common variant associated with prostate cancer in European and African populations.
Amundadottir LT, Sulem P, Gudmundsson J, Helgason A, Baker A, Agnarsson BA, Sigurdsson A, Benediktsdottir KR, Cazier JB, Sainz J, Jakobsdottir M, Kostic J, Magnusdottir DN, Ghosh S, Agnarsson K, Birgisdottir B, Le Roux L, Olafsdottir A, Blondal T, Andresdottir M, Gretarsdottir OS, Bergthorsson JT, Gudbjartsson D, Gylfason A, Thorleifsson G, Manolescu A, Kristjansson K, Geirsson G, Isaksson H, Douglas J, Johansson JE, Bälter K, Wiklund F, Montie JE, Yu X, Suarez BK, Ober C, Cooney KA, Gronberg H, Catalona WJ, Einarsson GV, Barkardottir RB, Gulcher JR, Kong A, Thorsteinsdottir U, Stefansson K.
(2006) Nat Genet. 38(6):652-8. Epub 2006 May 7. PMID: 16682969

Sex-specific genetic architecture of asthma-associated quantitative trait loci in a founder population.
Ober C, Pan L, Phillips N, Parry R, Kurina LM.
(2006) Curr Allergy Asthma Rep. 6(3):241-6. PMID: 16579875

Variation in the type I interferon gene cluster on 9p21 influences susceptibility to asthma and atopy.
Chan A, Newman DL, Shon AM, Schneider DH, Kuldanek S, Ober C.
(2006) Genes Immun. 7(2):169-78. PMID: 16437122

Asthma genetics the long and winding road to gene discovery.
Ober C, Hoffjan S.
(2006) Genes Immun. 7(2):95-100. Review. PMID: 16395390

The sex-specific genetic architecture of quantitative traits in humans.
Weiss LA, Pan L, Abney M, Ober C.
(2006) Nat Genet. 38(2):218-22. Epub 2006 Jan 22. PMID: 16429159

A genome-wide search for quantitative trait loci contributing to variation in seasonal pollen reactivity.
Blumenthal MN, Langefeld CD, Barnes KC, Ober C, Meyers DA, King RA, Beaty TH, Beck SR, Bleecker ER, Rich SS; Collaborative Study on the Genetics of Asthma.
(2006) J Allergy Clin Immunol. 117(1):79-85. PMID: 16387588

Variation in conserved non-coding sequences on chromosome 5q and susceptibility to asthma and atopy.
Donfack J, Schneider DH, Tan Z, Kurz T, Dubchak I, Frazer KA, Ober C.
(2005) Respir Res. 6:145. PMID: 16336695

Rethinking genetic models of asthma: the role of environmental modifiers.
Ober C, Thompson EE.
(2005) Curr Opin Immunol. 17(6):670-8. Epub 2005 Oct 7. Review. PMID: 16214315

Evidence of balancing selection at the HLA-G promoter region.
Tan Z, Shon AM, Ober C.
(2005) Hum Mol Genet. 14(23):3619-28. Epub 2005 Oct 19. PMID: 16236759

HLA-G: an asthma gene on chromosome 6p.
Ober C.
(2005) Immunol Allergy Clin North Am. 25(4):669-79. PMID: 16257632

Multilocus linkage disequilibrium mapping by the decay of haplotype sharing with samples of related individuals.
Zhang J, Schneider D, Ober C, McPeek MS.
(2005) Genet Epidemiol. 29(2):128-40. PMID: 16049966

Cutting edge: polymorphisms in the ICOS promoter region are associated with allergic sensitization and Th2 cytokine production.
Shilling RA, Pinto JM, Decker DC, Schneider DH, Bandukwala HS, Schneider JR, Camoretti-Mercado B, Ober C, Sperling AI.
(2005) J Immunol. 175(4):2061-5. PMID: 16081771

Perspectives on the past decade of asthma genetics.
Ober C.
(2005) J Allergy Clin Immunol. 116(2):274-8. PMID: 16083779

Sex differences in the genetic basis of morning serum cortisol levels: genome-wide screen identifies two novel loci specific to women.
Kurina LM, Weiss LA, Graves SW, Parry R, Williams GH, Abney M, Ober C.
(2005) J Clin Endocrinol Metab. 90(8):4747-52. Epub 2005 Jun 7. PMID: 15941864

Variation in ITGB3 is associated with asthma and sensitization to mold allergen in four populations.
Weiss LA, Lester LA, Gern JE, Wolf RL, Parry R, Lemanske RF, Solway J, Ober C.
(2005) Am J Respir Crit Care Med. 172(1):67-73. Epub 2005 Apr 7. PMID: 15817799

Variation in ITGB3 has sex-specific associations with plasma lipoprotein(a) and whole blood serotonin levels in a population-based sample.
Weiss LA, Abney M, Parry R, Scanu AM, Cook EH Jr, Ober C.
(2005) Hum Genet. 117(1):81-7. Epub 2005 Apr 15. PMID: 15834589

HLA-G and immune tolerance in pregnancy.
Hunt JS, Petroff MG, McIntire RH, Ober C.
(2005) FASEB J. 19(7):681-93. Review. PMID: 15857883

Gene-environment interaction effects on the development of immune responses in the 1st year of life.
Hoffjan S, Nicolae D, Ostrovnaya I, Roberg K, Evans M, Mirel DB, Steiner L, Walker K, Shult P, Gangnon RE, Gern JE, Martinez FD, Lemanske RF, Ober C.
(2005) Am J Hum Genet. 76(4):696-704. Epub 2005 Feb 22. PMID: 15726497

Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21.
Nicolae D, Cox NJ, Lester LA, Schneider D, Tan Z, Billstrand C, Kuldanek S, Donfack J, Kogut P, Patel NM, Goodenbour J, Howard T, Wolf R, Koppelman GH, White SR, Parry R, Postma DS, Meyers D, Bleecker ER, Hunt JS, Solway J, Ober C.
(2005) Am J Hum Genet. 76(2):349-57. Epub 2004 Dec 20. PMID: 15611928

Sex-specific genetic architecture of whole blood serotonin levels.
Weiss LA, Abney M, Cook EH Jr, Ober C.
(2005) Am J Hum Genet. 76(1):33-41. Epub 2004 Nov 3. PMID: 15526234

Human body scents: conscious perceptions and biological effects.
McClintock MK, Bullivant S, Jacob S, Spencer N, Zelano B, Ober C.
(2005) Chem Senses. 30 Suppl 1:i135-7. No abstract available. PMID: 15738077

Testing for Hardy-Weinberg equilibrium in samples with related individuals.
Bourgain C, Abney M, Schneider D, Ober C, McPeek MS.
(2004) Genetics. 168(4):2349-61. Epub 2004 Sep 15. PMID: 15371359

Genome-wide association study identifies ITGB3 as a QTL for whole blood serotonin.
Weiss LA, Veenstra-Vanderweele J, Newman DL, Kim SJ, Dytch H, McPeek MS, Cheng S, Ober C, Cook EH Jr, Abney M.
(2004) Eur J Hum Genet. 12(11):949-54. PMID: 15292919

The role of environmental tobacco smoke in genetic susceptibility to asthma.
Kurz T, Ober C.
(2004) Curr Opin Allergy Clin Immunol. 4(5):335-9. Review. PMID: 15349030

Inheritance of most X-linked traits is not dominant or recessive, just X-linked.
Dobyns WB, Filauro A, Tomson BN, Chan AS, Ho AW, Ting NT, Oosterwijk JC, Ober C.
(2004) Am J Med Genet A. 129A(2):136-43. PMID: 15316978

Are common disease susceptibility alleles the same in outbred and founder populations?
Newman DL, Hoffjan S, Bourgain C, Abney M, Nicolae RI, Profits ET, Grow MA, Walker K, Steiner L, Parry R, Reynolds R, McPeek MS, Cheng S, Ober C.
(2004) Eur J Hum Genet. 12(7):584-90. PMID: 15100713

Best linear unbiased allele-frequency estimation in complex pedigrees.
McPeek MS, Wu X, Ober C.
(2004) Biometrics. 60(2):359-67. PMID: 15180661

Genome scan for loci linked to mite sensitivity: the Collaborative Study on the Genetics of Asthma (CSGA).
Blumenthal MN, Ober C, Beaty TH, Bleecker ER, Langefeld CD, King RA, Lester L, Cox N, Barnes K, Togias A, Mathias R, Meyers DA, Oetting W, Rich SS; CSGA.
(2004) Genes Immun. 5(3):226-31. PMID: 15029235

Does HLA-dependent chimerism underlie the pathogenesis of juvenile dermatomyositis?
Reed AM, McNallan K, Wettstein P, Vehe R, Ober C.
(2004) J Immunol. 172(8):5041-6. PMID: 15067086

Genetic variation in immunoregulatory pathways and atopic phenotypes in infancy.
Hoffjan S, Ostrovnaja I, Nicolae D, Newman DL, Nicolae R, Gangnon R, Steiner L, Walker K, Reynolds R, Greene D, Mirel D, Gern JE, Lemanske RF Jr, Ober C.
(2004) J Allergy Clin Immunol. 113(3):511-8. PMID: 15007355

Effects of dog ownership and genotype on immune development and atopy in infancy.
Gern JE, Reardon CL, Hoffjan S, Nicolae D, Li Z, Roberg KA, Neaville WA, Carlson-Dakes K, Adler K, Hamilton R, Anderson E, Gilbertson-White S, Tisler C, Dasilva D, Anklam K, Mikus LD, Rosenthal LA, Ober C, Gangnon R, Lemanske RF Jr.
(2004) J Allergy Clin Immunol. 113(2):307-14. PMID: 14767447

Evidence for extensive transmission distortion in the human genome.
Zöllner S, Wen X, Hanchard NA, Herbert MA, Ober C, Pritchard JK.
(2004) Am J Hum Genet. 74(1):62-72. Epub 2003 Dec 15. PMID: 14681832

A genome-wide search for allergic response (atopy) genes in three ethnic groups: Collaborative Study on the Genetics of Asthma.
Blumenthal MN, Langefeld CD, Beaty TH, Bleecker ER, Ober C, Lester L, Lange E, Barnes KC, Wolf R, King RA, Solway J, Oetting W, Meyers DA, Rich SS.
(2004) Hum Genet. 114(2):157-64. Epub 2003 Oct 25. PMID: 14586638

Prodromal angina reduces infarcted mass less in interventionally reperfused than in thrombolysed myocardial infarction.
Ober MC, Ober C, Hagău A, Moţ S, Iancu A, Literat S, Căpâlneanu R.
(2004) Rom J Intern Med. 42(3):533-43. PMID: 16370052

Association studies for asthma and atopic diseases: a comprehensive review of the literature.
Hoffjan S, Nicolae D, Ober C.
(2003) Respir Res. 4:14. Print 2003. Review. PMID: 14748924

Immunogenicity of the soluble isoforms of HLA-G.
Hunt JS, Pace JL, Morales PJ, Ober C.
(2003) Mol Hum Reprod. 9(11):729-35. PMID: 14561816

Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus.
Bourgain C, Hoffjan S, Nicolae R, Newman D, Steiner L, Walker K, Reynolds R, Ober C, McPeek MS.
(2003) Am J Hum Genet. 73(3):612-26. Epub 2003 Aug 15. PMID: 12929084

Variation in the HLA-G promoter region influences miscarriage rates.
Ober C, Aldrich CL, Chervoneva I, Billstrand C, Rahimov F, Gray HL, Hyslop T.
(2003) Am J Hum Genet. 72(6):1425-35. Epub 2003 Apr 29. PMID: 12721954

Pregnancy outcome in recurrent miscarriage patients with skewed X chromosome inactivation.
Sullivan AE, Lewis T, Stephenson M, Odem R, Schreiber J, Ober C, Branch DW.
(2003) Obstet Gynecol. 101(6):1236-42. PMID: 12798530

Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure.
Colilla S, Nicolae D, Pluzhnikov A, Blumenthal MN, Beaty TH, Bleecker ER, Lange EM, Rich SS, Meyers DA, Ober C, Cox NJ; Collaborative Study for the Genetics of Asthma.
(2003) J Allergy Clin Immunol. 111(4):840-6. PMID: 12704367

Sequence variation in the promoter region of the cholinergic receptor muscarinic 3 gene and asthma and atopy.
Donfack J, Kogut P, Forsythe S, Solway J, Ober C.
(2003) J Allergy Clin Immunol. 111(3):527-32. PMID: 12642833

Major loci influencing serum triglyceride levels on 2q14 and 9p21 localized by homozygosity-by-descent mapping in a large Hutterite pedigree.
Newman DL, Abney M, Dytch H, Parry R, McPeek MS, Ober C.
(2003) Hum Mol Genet. 12(2):137-44. PMID: 12499394

Present status on the genetic studies of asthma.
Hoffjan S, Ober C.
(2002) Curr Opin Immunol. 14(6):709-17. Review. PMID: 12413520

Linkage disequilibrium and age estimates of a deletion polymorphism (1597DeltaC) in HLA-G suggest non-neutral evolution.
Aldrich C, Wambebe C, Odama L, Di Rienzo A, Ober C.
(2002) Hum Immunol. 63(5):405-12. PMID: 11975984

Quantitative-trait homozygosity and association mapping and empirical genomewide significance in large, complex pedigrees: fasting serum-insulin level in the Hutterites.
Abney M, Ober C, McPeek MS.
(2002) Am J Hum Genet. 70(4):920-34. Epub 2002 Mar 4. PMID: 11880950

Paternally inherited HLA alleles are associated with women's choice of male odor.
Jacob S, McClintock MK, Zelano B, Ober C.
(2002) Nat Genet. 30(2):175-9. Epub 2002 Jan 22. PMID: 11799397

Missing data in haplotype analysis: a study on the MILC method.
Bourgain C, Genin E, Ober C, Clerget-Darpoux F.
(2002) Ann Hum Genet. 66(Pt 1):99-108. PMID: 12022148

Three polymorphisms in the 3' UTR of the TRAIL (TNF-related apoptosis-inducing ligand) gene.
Gray HL, Sorensen EL, Hunt JS, Ober C.
(2001) Genes Immun. 2(8):469-70. PMID: 11781716

HLA-G genotypes and pregnancy outcome in couples with unexplained recurrent miscarriage.
Aldrich CL, Stephenson MD, Karrison T, Odem RR, Branch DW, Scott JR, Schreiber JR, Ober C.
(2001) Mol Hum Reprod. 7(12):1167-72. PMID: 11719594

The importance of genealogy in determining genetic associations with complex traits.
Newman DL, Abney M, McPeek MS, Ober C, Cox NJ.
(2001) Am J Hum Genet. 69(5):1146-8. No abstract available. PMID: 11590549

The genetic dissection of complex traits in a founder population.
Ober C, Abney M, McPeek MS.
(2001) Am J Hum Genet. 69(5):1068-79. Epub 2001 Oct 3. Erratum in: Am J Hum Genet 2002 Jan;70(1):284. PMID: 11590547

Ethnic differences in asthma and associated phenotypes: collaborative study on the genetics of asthma.
Lester LA, Rich SS, Blumenthal MN, Togias A, Murphy S, Malveaux F, Miller ME, Dunston GM, Solway J, Wolf RL, Samet JM, Marsh DG, Meyers DA, Ober C, Bleecker ER; Collaborative Study on the Genetics of Asthma.
(2001) J Allergy Clin Immunol. 108(3):357-62. PMID: 11544453

Genomewide screen and identification of gene-gene interactions for asthma-susceptibility loci in three U.S. populations: collaborative study on the genetics of asthma.
Xu J, Meyers DA, Ober C, Blumenthal MN, Mellen B, Barnes KC, King RA, Lester LA, Howard TD, Solway J, Langefeld CD, Beaty TH, Rich SS, Bleecker ER, Cox NJ; Collaborative Study on the Genetics of Asthma.
(2001) Am J Hum Genet. 68(6):1437-46. Epub 2001 May 10. PMID: 11349227

Broad and narrow heritabilities of quantitative traits in a founder population.
Abney M, McPeek MS, Ober C.
(2001) Am J Hum Genet. 68(5):1302-7. Epub 2001 Apr 10. PMID: 11309690

A population genetics study of single nucleotide polymorphisms in the interleukin 4 receptor alpha (IL4RA) gene.
Wu X, Di Rienzo A, Ober C.
(2001) Genes Immun. 2(3):128-34. PMID: 11426321

A novel polymorphism in the 5' promoter region of the human interleukin-4 receptor alpha-chain gene is associated with decreased soluble interleukin-4 receptor protein levels.
Hackstein H, Hecker M, Kruse S, Bohnert A, Ober C, Deichmann KA, Bein G.
(2001) Immunogenetics. 53(4):264-9. PMID: 11491529

Genome-wide linkage analyses of total serum IgE using variance components analysis in asthmatic families.
Mathias RA, Freidhoff LR, Blumenthal MN, Meyers DA, Lester L, King R, Xu JF, Solway J, Barnes KC, Pierce J, Stine OC, Togias A, Oetting W, Marshik PL, Hetmanski JB, Huang SK, Ehrlich E, Dunston GM, Malveaux F, Banks-Schlegel S, Cox NJ, Bleecker E, Ober C, Beaty TH, Rich SS; CSGA (Collaborative Study of the Genetics of Asthma).
(2001) Genet Epidemiol. 20(3):340-55. PMID: 11255243

Susceptibility genes in asthma and allergy.
Ober C.
(2001) Curr Allergy Asthma Rep. 1(2):174-9. Review. PMID: 11899300

Description of three data sets: Collaborative Study on the Genetics of Asthma (CSGA), the German Affected-Sib-Pair Study, and the Hutterites of South Dakota.
Meyers DA, Wjst M, Ober C.
(2001) Genet Epidemiol. 21 Suppl 1:S4-8. PMID: 11793707

A second-generation genomewide screen for asthma-susceptibility alleles in a founder population.
Ober C, Tsalenko A, Parry R, Cox NJ.
(2000) Am J Hum Genet. 67(5):1154-62. Epub 2000 Oct 5. PMID: 11022011

HLA-G in reproduction: studies on the maternal-fetal interface.
Hunt JS, Petroff MG, Morales P, Sedlmayr P, Geraghty DE, Ober C.
(2000) Hum Immunol. 61(11):1113-7. Review. PMID: 11137215

Soluble HLA-G circulates in maternal blood during pregnancy.
Hunt JS, Jadhav L, Chu W, Geraghty DE, Ober C.
(2000) Am J Obstet Gynecol. 183(3):682-8. PMID: 10992193

Cross-species amplification, non-invasive genotyping, and non-Mendelian inheritance of human STRPs in Savannah baboons.
Smith KL, Alberts SC, Bayes MK, Bruford MW, Altmann J, Ober C.
(2000) Am J Primatol. 51(4):219-27. PMID: 10941438

beta(2)-adrenergic receptor Arg16/Arg16 genotype is associated with reduced lung function, but not with asthma, in the Hutterites.
Summerhill E, Leavitt SA, Gidley H, Parry R, Solway J, Ober C.
(2000) Am J Respir Crit Care Med. 162(2 Pt 1):599-602. PMID: 10934093

Polymorphisms in the HLA-linked olfactory receptor genes in the Hutterites.
Eklund AC, Belchak MM, Lapidos K, Raha-Chowdhury R, Ober C.
(2000) Hum Immunol. 61(7):711-7. PMID: 10880742

Contributing factors to the pathobiology. The genetics of asthma.
Ober C, Moffatt MF.
(2000) Clin Chest Med. 21(2):245-61. Review. PMID: 10907586

HLA-DRB1*01 alleles are associated with sensitization to cockroach allergens.
Donfack J, Tsalenko A, Hoki DM, Parry R, Solway J, Lester LA, Ober C.
(2000) J Allergy Clin Immunol. 105(5):960-6. PMID: 10808177

A null mutation in HLA-G is not associated with preeclampsia or intrauterine growth retardation.
Aldrich C, Verp MS, Walker MA, Ober C.
(2000) J Reprod Immunol. 47(1):41-8. PMID: 10779589

Estimation of variance components of quantitative traits in inbred populations.
Abney M, McPeek MS, Ober C.
(2000) Am J Hum Genet. 66(2):629-50. PMID: 10677322

Variation in the interleukin 4-receptor alpha gene confers susceptibility to asthma and atopy in ethnically diverse populations.
Ober C, Leavitt SA, Tsalenko A, Howard TD, Hoki DM, Daniel R, Newman DL, Wu X, Parry R, Lester LA, Solway J, Blumenthal M, King RA, Xu J, Meyers DA, Bleecker ER, Cox NJ.
(2000) Am J Hum Genet. 66(2):517-26. PMID: 10677312

A robust test for assortative mating.
Génin E, Ober C, Weitkamp L, Thomson G.
(2000) Eur J Hum Genet. 8(2):119-24. PMID: 10757643

Polymorphic microsatellite markers within the MHC of Peromyscus polionotus.
Eklund AC, Ober C.
(2000) Hereditas. 133(2):179-81. No abstract available. PMID: 11338432

Genome-wide screen for atopy susceptibility alleles in the Hutterites.
Ober C, Tsalenko A, Willadsen S, Newman D, Daniel R, Wu X, Andal J, Hoki D, Schneider D, True K, Schou C, Parry R, Cox N.
(1999) Clin Exp Allergy. 29 Suppl 4:11-5. PMID: 10641559

Determination of Duffy genotypes in three populations of African descent using PCR and sequence-specific oligonucleotides.
Nickel RG, Willadsen SA, Freidhoff LR, Huang SK, Caraballo L, Naidu RP, Levett P, Blumenthal M, Banks-Schlegel S, Bleecker E, Beaty T, Ober C, Barnes KC.
(1999) Hum Immunol. 60(8):738-42. PMID: 10439320

Mononuclear-cell immunisation in prevention of recurrent miscarriages: arandomised trial.
Ober C, Karrison T, Odem RR, Barnes RB, Branch DW, Stephenson MD, Baron B, Walker MA, Scott JR, Schreiber JR.
(1999) Lancet. 354(9176):365-9. PMID: 10437864

Ancestral and recombinant 16-locus HLA haplotypes in the Hutterites.
Weitkamp LR, Ober C.
(1999) Immunogenetics. 49(6):491-7. PMID: 10380692

Studies of HLA, fertility and mate choice in a human isolate.
Ober C.
(1999) Hum Reprod Update. 5(2):103-7. Review. PMID: 10336015

Inbreeding effects on fertility in humans: evidence for reproductive compensation.
Ober C, Hyslop T, Hauck WW.
(1999) Am J Hum Genet. 64(1):225-31. PMID: 9915962

Effect of inbreeding avoidance on Hardy-Weinberg expectations: examples of neutral and selected loci.
Robertson A, Charlesworth D, Ober C.
(1999) Genet Epidemiol. 17(3):165-73. PMID: 10446464

The CTLA-4 gene is expressed in placental fibroblasts.
Kaufman KA, Bowen JA, Tsai AF, Bluestone JA, Hunt JS, Ober C.
(1999) Mol Hum Reprod. 5(1):84-7. PMID: 10050667

HLA-H: a pseudogene with increased variation due to balancing selection at neighboring loci.
Grimsley C, Mather KA, Ober C.
(1998) Mol Biol Evol. 15(12):1581-8. PMID: 9866194

Transmission disequilibrium of maternally-inherited CTLA-4 microsatellite alleles in idiopathic recurrent miscarriage.
Tsai AF, Kaufman KA, Walker MA, Karrison TG, Odem RR, Barnes RB, Scott JR, Schreiber JR, Stephenson MD, Ober C.
(1998) J Reprod Immunol. 40(2):147-57. PMID: 9881742

Recurrent miscarriage (REMIS) study: how should data from women who do not become pregnant be handled?
Karrison TG, Ober C.
(1998) Control Clin Trials. 19(5):430-9. PMID: 9741864

HLA-G polymorphisms: ethnic differences and implications for potential molecule function.
van der Ven K, Skrablin S, Ober C, Krebs D.
(1998) Am J Reprod Immunol. 40(3):145-57. Review. PMID: 9764358

Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma.
Ober C, Cox NJ, Abney M, Di Rienzo A, Lander ES, Changyaleket B, Gidley H, Kurtz B, Lee J, Nance M, Pettersson A, Prescott J, Richardson A, Schlenker E, Summerhill E, Willadsen S, Parry R.
(1998) Hum Mol Genet. 7(9):1393-8. PMID: 9700192

Expression and cytogenetic localization of the human SM22 gene (TAGLN).
Camoretti-Mercado B, Forsythe SM, LeBeau MM, Espinosa R 3rd, Vieira JE, Halayko AJ, Willadsen S, Kurtz B, Ober C, Evans GA, Thweatt R, Shapiro S, Niu Q, Qin Y, Padrid PA, Solway J.
(1998) Genomics. 49(3):452-7. PMID: 9615232

Immunogenetic studies in families of children with juvenile dermatomyositis.
Reed AM, Pachman LM, Hayford J, Ober C.
(1998) J Rheumatol. 25(5):1000-2. PMID: 9598907

The genetics of asthma. Mapping genes for complex traits in founder populations.
Ober C, Cox NJ.
(1998) Clin Exp Allergy. 28 Suppl 1:101-5; discussion 108-10. No abstract available. PMID: 9641605

HLA-G1 protein expression is not essential for fetal survival.
Ober C, Aldrich C, Rosinsky B, Robertson A, Walker MA, Willadsen S, Verp MS, Geraghty DE, Hunt JS.
(1998) Placenta. 19(2-3):127-32. PMID: 9548178

Microchimerism and HLA-compatible relationships of pregnancy in scleroderma.
Nelson JL, Furst DE, Maloney S, Gooley T, Evans PC, Smith A, Bean MA, Ober C, Bianchi DW.
(1998) Lancet. 351(9102):559-62. PMID: 9492775

Do genetics play a role in the pathogenesis of asthma?
Ober C.
(1998) J Allergy Clin Immunol. 101(2 Pt 2):S417-20. Review. No abstract available. PMID: 9500742

HLA and pregnancy: the paradox of the fetal allograft.
Ober C.
(1998) Am J Hum Genet. 62(1):1-5. Review. No abstract available. PMID: 9443885

Human leukocyte antigen matching and fetal loss: results of a 10 year prospective study.
Ober C, Hyslop T, Elias S, Weitkamp LR, Hauck WW.
(1998) Hum Reprod. 13(1):33-8. PMID: 9512225

Evaluating the role of Th0 and Th1 clones in autoimmune thyroid disease by use of Hu-SCID chimeras.
Fisfalen ME, Soltani K, Kaplan E, Palmer EM, van Seventer GA, Straus FH, Diaz M, Ober C, DeGroot LJ.
(1997) Clin Immunol Immunopathol. 85(3):253-64. PMID: 9400625

HLA-G polymorphisms: neutral evolution or novel function?
Ober C, Aldrich CL.
(1997) J Reprod Immunol. 36(1-2):1-21. Review. PMID: 9430736

Thyrotropin-receptor and thyroid peroxidase-specific T cell clones and their cytokine profile in autoimmune thyroid disease.
Fisfalen ME, Palmer EM, Van Seventer GA, Soltani K, Sawai Y, Kaplan E, Hidaka Y, Ober C, DeGroot LJ.
(1997) J Clin Endocrinol Metab. 82(11):3655-63. PMID: 9360522

HLA and mate choice in humans.
Ober C, Weitkamp LR, Cox N, Dytch H, Kostyu D, Elias S.
(1997) Am J Hum Genet. 61(3):497-504. PMID: 9326314

A genome-wide search for asthma susceptibility loci in ethnically diverse populations. The Collaborative Study on the Genetics of Asthma (CSGA).
Collaborative Study on the Genetics of Asthma (CSGA) [C. Ober, corresponding author].
(1997) Nat Genet. 15(4):389-92. PMID: 9090385

Immunogenetics of reproduction: an overview.
Ober C, van der Ven K.
(1997) Curr Top Microbiol Immunol. 222:1-23. Review. No abstract available. PMID: 9257483

Population genetic studies of HLA-E: evidence for selection.
Grimsley C, Ober C.
(1997) Hum Immunol. 52(1):33-40. PMID: 9021407

Population genetic studies of HLA-G: allele frequencies and linkage disequilibrium with HLA-A1.
Ober C, Rosinsky B, Grimsley C, van der Ven K, Robertson A, Runge A.
(1996) J Reprod Immunol. 32(2):111-23. Erratum in: J Reprod Immunol 1997 Apr;33(1):89-90. PMID: 9023816

Cystic fibrosis mutation screening in healthy men with reduced sperm quality.
van der Ven K, Messer L, van der Ven H, Jeyendran RS, Ober C.
(1996) Hum Reprod. 11(3):513-7. PMID: 8671256

HLA and fertility.
Ober C.
(1995) Am J Hum Genet. 57(5):1242-3. No abstract available. PMID: 7485176

Collaborative studies on the genetics of asthma--National Heart, Lung and Blood Institute.
Blumenthal MN, Banks-Schlegel S, Bleecker ER, Marsh DG, Ober C.
(1995) Clin Exp Allergy. 25 Suppl 2:29-32. No abstract available. PMID: 8590337

Current topic: HLA and reproduction: lessons from studies in the Hutterites.
Ober C.
(1995) Placenta. 16(7):569-77. PMID: 8577656

HLA-DQA1 and HLA-DQB1 haplotypes in aborted fetuses and couples with recurrent spontaneous abortion.
Steck T, van der Ven K, Kwak J, Beer A, Ober C.
(1995) J Reprod Immunol. 29(2):95-104. PMID: 7500323

Prioritizing asthma research: the need to investigate childhood asthma.
Geppert EF, Lester LA, Ober C.
(1995) Am J Respir Crit Care Med. 151(5):1294-5. No abstract available. PMID: 7735577

Extended HLA profile of an inbred isolate: the Schmiedeleut Hutterites of South Dakota.
Dawson DV, Ober C, Kostyu DD.
(1995) Genet Epidemiol. 12(1):47-62. PMID: 7713400

HLA-G polymorphisms in African Americans.
van der Ven K, Ober C.
(1994) J Immunol. 153(12):5628-33. PMID: 7989762

Analysis of HLA haplotype segregation in the Schmiedeleut Hutterites of South Dakota.
Bryttan JM, Kostyu DD, Ober C, Elias S, Dawson DV.
(1994) Hum Hered. 44(4):181-90. PMID: 8056430

Delta F508 genotype does not predict disease severity in an ethnically diverse cystic fibrosis population.
Lester LA, Kraut J, Lloyd-Still J, Karrison T, Mott C, Billstrand C, Lemke A, Ober C.
(1994) Pediatrics. 93(1):114-8. PMID: 7505422

MHC class II compatibility in aborted fetuses and term infants of couples with recurrent spontaneous abortion.
Ober C, Steck T, van der Ven K, Billstrand C, Messer L, Kwak J, Beaman K, Beer A.
(1993) J Reprod Immunol. 25(3):195-207. PMID: 8207709

Autoantibodies and pregnancy history in a healthy population.
Ober C, Karrison T, Harlow L, Elias S, Gleicher N.
(1993) Am J Obstet Gynecol. 169(1):143-7. PMID: 8333442

Deficit of HLA homozygotes in a Caucasian isolate.
Kostyu DD, Dawson DV, Elias S, Ober C.
(1993) Hum Immunol. 37(3):135-42. PMID: 8244776

Maternal-fetal histocompatibility in intrauterine growth retarded and normal weight babies.
Verp MS, Sibul M, Billstrand C, Bellen G, Hsu M, Ober C.
(1993) Am J Reprod Immunol. 29(4):195-8. PMID: 8397808

Sex-biased lactational duration in a human population and its reproductive costs.
Margulis SW, Altmann J, Ober C.
(1993) Behav Ecol Sociobiol. 32(1):41-5. PMID: 12286204

Ethnic heterogeneity and cystic fibrosis transmembrane regulator (CFTR) mutation frequencies in Chicago-area CF families.
Ober C, Lester LA, Mott C, Billstrand C, Lemke A, van der Ven K, Marcus S, Kraut J, Lloyd-Still J, Booth C.
(1992) Am J Hum Genet. 51(6):1344-8. PMID: 1281385

Increased risk for polycystic ovary syndrome associated with human leukocyte antigen DQA1*0501.
Ober C, Weil S, Steck T, Billstrand C, Levrant S, Barnes R.
(1992) Am J Obstet Gynecol. 167(6):1803-6. PMID: 1471701

Chimerism as the etiology of a 46,XX/46,XY fertile true hermaphrodite.
Verp MS, Harrison HH, Ober C, Oliveri D, Amarose AP, Lindgren V, Talerman A.
(1992) Fertil Steril. 57(2):346-9. PMID: 1735486

Decreased fecundability in Hutterite couples sharing HLA-DR.
Ober C, Elias S, Kostyu DD, Hauck WW.
(1992) Am J Hum Genet. 50(1):6-14. PMID: 1729895

The maternal-fetal relationship in human pregnancy: an immunogenetic perspective.
Ober C.
(1992) Exp Clin Immunogenet. 9(1):1-14. Review. PMID: 1642900

Molecular genetic studies of major histocompatibility complex genes in children with juvenile dermatomyositis: increased risk associated with HLA-DQA1 *0501.
Reed AM, Pachman L, Ober C.
(1991) Hum Immunol. 32(4):235-40. PMID: 1783570

Correlation of phenotypic and genetic heterogeneity in cystic fibrosis: variability in sweat electrolyte levels contributes to heterogeneity and is increased with the XV-2c/KM19 B haplotype.
Witt M, Erickson RP, Ober C, Howatt WF, Farber R.
(1991) Am J Med Genet. 39(2):137-43. PMID: 2063915

Delayed diagnosis of pseudohermaphroditism on stored blood spot.
Verp MS, Ober C, Oliveri DR, Israel J.
(1991) Lancet. 337(8748):1037. No abstract available. PMID: 1673185

Identification of a serum protein polymorphism via two-dimensional electrophoresis. Family and population studies in two genetically isolated groups: North American Hutterites and Australian aborigines.
Harrison H, Miller K, Ober C, Refetoff S, Dick M, Elias S.
(1991) Am J Hum Genet. 48(2):362-9. PMID: 1990842

Statistical analysis of outcomes from repeated pregnancies: effects of HLA sharing on fetal loss rates.
Hauck WW, Ober C.
(1991) Genet Epidemiol. 8(3):187-97. PMID: 1955153

Translocations are infrequent among couples having repeated spontaneous abortions but no other abnormal pregnancies.
Simpson JL, Meyers CM, Martin AO, Elias S, Ober C.
(1989) Fertil Steril. 51(5):811-4. PMID: 2707455

Increased risk for gestational diabetes mellitus associated with insulin receptor and insulin-like growth factor II restriction fragment length polymorphisms.
Ober C, Xiang KS, Thisted RA, Indovina KA, Wason CJ, Dooley S.
(1989) Genet Epidemiol. 6(5):559-69. PMID: 2574127

HLA sharing and fertility in Hutterite couples: evidence for prenatal selection against compatible fetuses.
Ober C, Elias S, O'Brien E, Kostyu DD, Hauck WW, Bombard A.
(1988) Am J Reprod Immunol Microbiol. 18(4):111-5. PMID: 3245544

Autoimmune etiology in premature ovarian failure.
LaBarbera AR, Miller MM, Ober C, Rebar RW.
(1988) Am J Reprod Immunol Microbiol. 16(3):115-22. Review. No abstract available. PMID: 3289410

Studies of cystic fibrosis in Hutterite families by using linked DNA probes.
Ober C, Bombard A, Dhaliwal R, Elias S, Fagan J, Laffler TG, Martin AO, Rosinsky B.
(1987) Am J Hum Genet. 41(6):1145-51. PMID: 3479902

Restriction fragment length polymorphisms of the insulin gene hypervariable region in gestational onset diabetes mellitus.
Ober C, Wason CJ, Andrew K, Dooley S.
(1987) Am J Obstet Gynecol. 157(6):1364-8. PMID: 2892412

Prenatal effects of maternal-fetal HLA compatibility.
Ober C, Simpson JL, Ward M, Radvany RM, Andersen R, Elias S, Sabbagha R.
(1987) Am J Reprod Immunol Microbiol. 15(4):141-9. PMID: 3481221

The human sex ratio: increase in first-born males to parents with shared HLA-DR antigens.
Radvany RM, Vaisrub N, Ober C, Patel KM, Hecht F.
(1987) Tissue Antigens. 29(1):34-42. PMID: 3590144

Maternal serum alpha-fetoprotein screening: low and high values for detection of genetic abnormalities.
Simpson JL, Baum LD, Marder R, Elias S, Ober C, Martin AO.
(1986) Am J Obstet Gynecol. 155(3):593-7. PMID: 2428249

Diabetes mellitus: preventing anomalies through maternal metabolic intervention.
Ober C, Simpson JL.
(1986) Clin Obstet Gynecol. 29(3):558-68. No abstract available. PMID: 2428552

Gestational diabetes mellitus: a syndrome with phenotypic and genotypic heterogeneity.
Freinkel N, Metzger BE, Phelps RL, Simpson JL, Martin AO, Radvany R, Ober C, Dooley SL, Depp RO, Belton A.
(1986) Horm Metab Res. 18(7):427-30. Review. PMID: 3527923

Increased male-to-female sex ratio among HLA-DR compatible pregnancies.
Ober C, Simpson JL, Radvany R.
(1985) Lancet. 1(8431):761. No abstract available. PMID: 2858031

Frequency of diabetes mellitus in mothers of probands with gestational diabetes: possible maternal influence on the predisposition to gestational diabetes.
Martin AO, Simpson JL, Ober C, Freinkel N.
(1985) Am J Obstet Gynecol. 151(4):471-5. PMID: 3976747

Ober Lab Address

University of Chicago
Department of Human Genetics
920 E. 58th St. CLSC 431F
Chicago, IL 60637

Tel: (773) 702-5898
Fax: (773) 834-0505


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